The H3K27me2/3 (11D1) Monoclonal Antibody from Bioss Inc. is a Mouse Monoclonal antibody to H3 clustered histone 1. This antibody recognizes Human antigen. The H3K27me2/3 (11D1) Monoclonal Antibody has been validated for the following applications: Dot Blot, and Western Blot.
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling